The 3 in the game title is based on the 3 floating towers in Avernus that launch imps in the intro cinematic.[/spoiler]
I wasn't referring to the logo; that three merely points to being the third in a series. I meant the actual loading screens; they specifically mention and name the Dead Three. You know, in the loading screen tips, "Remember, while your character does not have to eat, remember that you do. We don't want to loose any dedicated players" . There are only a handful of tips about the gameworld, including the war between Shar & Selune, it's already apparant that this will be important. As such, whilst we haven't uncovered anything of it, I suspect the Dead Three eventually become equally important.
I know what you were referring to. I was just adding that the 3 is shaped like the 3 floating Avernus towers.
The logo isn't just a Bhaal's skull that turns into a Mindflayer. It also has Avernus symbolism on it.