Other than occasionally having my toon automatically swing for an attack of opportunity I really couldn't say what other options are here for reactions. However, if players see popups as a problem they could also slow down time, similar to the slow turn based movement they already have, and give a chance to use a reaction that is in your list. Combat right now feels very static. I go...enemy goes and I wait 5 minutes for the 10 goblins to move in a row. Reactions are a great way to break this up and make it feel more alive. I just don't think they have implemented enough of them in a useful way so far. Maybe I'm missing something though so if you have a different experience other than some auto attack feature please let me know what else there is as far as the reaction system goes.