Nettie is a great example of doing things really wrong: If you want the peaceful/good solution you will have to pass 2-3 checks, or kill her. These are obvious, but the good way is incredibly hard. What you might not know is that you can also use a cauldron to brew your own antidote and you can steal it from her. You might also be able to just go and get healing elsewhere.
No, the Nettie situation is an example of how we as players need to think more about our actions! Its blindingly obvious that Nettie the apprentice druid is NOT going to be able to remove our tadpoles. So why does everyone ask her to do it? Because we are conditioned to believe that we should 'do everything' in games and that we will always be successful. BG3 is NOT like that!
There is no need to ask Nettie to help us. and there are multiple options to back out before things get serious.
And there is Zero need to kill her . . . even if you fail all the rolls. There is a Knockout option in combat (why does no one ever remember this?)
Nettie ending up dead is the result of the player making multiple poor choices, not dice rolls.
Unless of course you want to kill Nettie . . which is a valid choice. The druids are in theory neutral but are acting very hostile toward outsiders. They don't exactly earn any goodwill.