I've seen several people mention this about saving the tiefling girl. I've succeeded at saving her 1 time in 4 so far. Someone can feel free to correct me if I'm wrong but I think the only thing that I got from saving her was a very minor amount of gold from the parents, like 50g or something. It certainly wasn't anything amazing or even relevant or I would remember it better. It's certainly not a vital thing to do and in fact, the deck is stacked against you succeeding at it. I cannot understand why anyone would waste their time reloading the game over that.
The guy pinned under the timber in Waukeen's Rest is the same way. My current playthrough I succeeded in saving him (which is funny because I didn't even go in the room where he is at) and I got nothing. I may have gotten some xp, didn't notice. I wouldn't even have known I'd saved him except I noticed it in the quest log when I was looking for something else.
Both of those are side quests and minor ones at that. You're really not missing out on anything if you fail the rolls. The things that are integral to the main plot usually have very low DCs and/or let you re-roll if you fail or even better, you can use the parasite to make it where you are unable to fail by lowering the DC to 1.
I think maybe you misunderstood me? I wasn't speaking about the actual material rewards my character was missing out on. I was speaking about the empathy I felt toward the two characters, and the sense of futility/failure if I don't get to rescue them.
Maybe this makes me softhearted. I mean, I know she's not a real girl. But I can't help but feel like shit if I don't save her. I *want* to be as good of a person as possible when I play these games, and help as many people as I can.
That is admirable and that kind of empathy is something I don't see much from gamers these days. I want to save her too or else I wouldn't try but I don't want to save her bad enough to sit through the loading screens though. Kudos to you 
