The game is not that hard. Almost everything is dead but the myconids (goblins, druids, Tyr paladins, gnolls, etc.) and I:

1) Never save scummed
2) Didn't use barrelmancy
3) Elemental arrows
4) Any potions except heal potions
5) Long rested only when almost every character's spells and abilities were spent
6) Maybe three deaths (mostly from being shoved into an auto-kill zone)

I did use food to heal up, and some fights I think I had some lucky rolls (e.g Githyanki), but overall not hard at all.

My party was:

Drow Cleric (Light) using a shield and Shield Mastery perk
Astarion (the melee version, not spell caster)
Gale (who only got the OP magic missile necklace for the last three battles I did: Zhentarim and Hag battles)
Lae'zel (2H battlemaster, +2 stats instead of perk)