Personally I miss the randomized loot from DOS2, gave the game more replayability in my opinion.
Experience tells me that there's no changing other people's minds about this stuff, but my counterargument is that it didn't gave even enough "playability" to sustain a single playthrough.
The mere fact that there weren't actual good and memorable items in the game and every piece of equipment was:
1) randomly generated
2) same-y and lacking identity
3) quickly outpaced by the next thing barely one level later so never valuable on the long term
4) droppable at any given even moment looting a random crate regardless of what you accomplished
...made finding loot feel like compulsively collecting and sorting garbage in your inventory. And made it feel like nothing you did could even matter, since the reward for completing a quest or killing a boss was often worse than the random shit you found on a crate.
And let's not mention when bad luck with the random drops acted in contrast with the build you were attempting to carry.
Conversely, years later I can still remember where to find some memorable items in BG2 and every time I replayed the game across the years I had a lot of fun even just with planning the perfect build/party composition based on making the most use of the best artifacts in the game.