I could reproduce this bug on two occassions so far. One conversation in the owlbear cave with Shadowheart. Party was standing near water and during the cutscene Shadowheart ended up underwater. Since she is a very talented gal, this didn't stop her from holding a conversation, but it would freeze the persuasion dice roll each time. Moved the party, cutscene worked properly, no freeze.
Second conversation was with Astarion, when he tries to snack on the PC in the camp. He was wearing a helmet that for some reason during that cutscene was clipping into his head (making him look like a an eldritch monstrosity :D). Again, the persuasion roll was freezing. Without the helmet the convo proceeded normally.
So I wonder whether this bug isn't due to how the cutscenes are animated.