dude arthritis perhaps its time to wrap up playing video games...maybe your age is effected by them...??? and stats kinda effect hand eye coordination agility is based upon whether or not you're agile and dexterous. no one claimed to think of this as fallout or elder scrolls, the latter which i have never played nor do i care to.
My young (I assume) friend, you better hope you still have the time and want to for playing video games when you get to your middle years and beyond. Don't give that person grief because they still enjoy something even though they are past the median age of participants.
That said, Anfindel is right and you are wrong. This game is not a twitch fest nor was it intended to be such. Look at the combat. Do you have to sit there and mouse click every time you want to swing your weapon? Do you have to circle strafe to get around to flank enemies? No and no. Why would you expect picking locks to be any different?