Originally Posted by Soul-Scar
As the title says,

1) Random encounters
2) Night and day cycle
3) Camping where you are, dungeon, woods etc.
4) No height advantage in combat
5) No enemy HP bloat
6) limited fast travel
7) less consumerbles for trash mobs
8) less ground effects
9) dice rolled attributes on character creation
10) food per character per day (camping requirements aka supplies)
11) More short rests
12) Traps, crafting and setting of (no limit)

1) No, they don't add anything meaningful to the game, just slow down your story progression
2) Maybe? Doesn't really matter to me - I'd rather have a solid schedule for NPC's during the day than split the effort in between night/day
3) No, although I hope the camp will follow us through the game, changing depending how far in the story we progressed.
4) Maybe? I don't mind advantage or +/- static value, but verticality should have a mechanical impact considering its prominence in BG3
5) Don't think there is that much bloat - sure the goblins have it, but treat them as re-skinned bandits. Gnolls, bugbears and other creatures seem more inline with their MM counterparts.
6) Hard No - why waste my irl time to walk through non-story content. You don't narrate every step of your party in 5e, so you effectively fast travel.
7) Maybe? Don't think the are that much of a pain.
8) Ground effects are fine, maybe a bit less of them. Granted, ray of frost shouldn't just create a ice surface, but otherwise I am ok with it.
9) Hard No - how do you plan to balance the game? A DM can scale encounters on if your PC rolled high/low stats, the game can't. And if you want to be powerful - lower the difficulty.
10) No, extra busy work
11) Yes, 2 at least
12) No, in 5e your traps are limited only by your creativity, whereas in BG3 they are limited by what the devs put in the game. So why have something that can never compare to pnp.