@Evil_it_Self
In 5e combat, ability checks are mostly reserved for:
-Str (Athletics) vs Str (Athletics) for Shoving
-Str (Athletics) vs Str (Athletics) or Dex (Acrobatics) for grappling.
-Dex (Stealth) checks for hiding
-Wis (Perception) for seeing hidden people
-Charisma (Persuasion/Intimidate) checks to convince the enemy to surrender

EDIT- @Topgoon gave a more detailed explanation than me, look at their post.

Idk how shoving works (and how/if grappling will work) in BG3, but if Larian matches 5e then these would be the cases for giving disadvantage to monster ability checks.

Disadvantage affects STs when the spell/ability specifically says it affects STs, yes. So not the hex spell. But, e.g., being restrained gives disadvantage on ST and attack rolls. Dodging makes enemies attack you with disadvange and you get advantage on dex STs. Etc

5e rules-as-written, being blinded does not affect STs. Again, idk how this works in BG3

Last edited by mrfuji3; 10/11/20 08:14 PM. Reason: mention Topgoon