Cyric (one of the Dead Three) holds the portfolio of Lies and a Trickery Domain. His interference can explain a lot.
For now, I'd say it would be nice to see a power play between the Dead Three (who may turn on each other easily, especially closer to the culmination), Shar, Vlaakith, Iolaum, and some devilish powers to boot. It's the one boiling pot with many turns and twists along the way. Or it is a wishful belief that Larian writers can hatch a truly epic plot and not get their wings cut in the process, by Hasbro or whoever.