Cyric (one of the Dead Three) holds the portfolio of Lies and a Trickery Domain. His interference can explain a lot.
The Dead Three includes Bane, Myrkul and Bhaal, not Cyric. Besides, by the time of BG3 events Cyric lost most of his portfolio (especially the part related to death) and is imprisoned in his plane.
My bad, thank you for correcting me. Was it in novels, or somewhere else? Who is holding the Portfolio of Lies now, then?
Edit: actually, that would be even more interesting, with Cyric being outside but still plotting, and acting through intermediaries. If he is still a Prince of Lies.