Take Wyll - he's got a sexy female cambion for a mistress/patron, flirts hard with both Lae'zel and Shadowheart, ignores Gale and Astarion, but at the party he (apparently) propositions a male PC exactly like a female one, with no prior indication that he'd be at all interested in a guy. That just looks odd to me.
I keep hearing that but I can't reproduce it. I can get Wyll to say he's sorry that I didn't choose him but if I F8 and ask him he says something like he doesn't feel the connection and has a tankard to keep him company.
I can also get to the party where no one is interested in the main character without problem -- in fact I think that will become the bigger problem in future because once I got too efficient on a play-through -- imagining I was really worried that this bomb inside my head would go off -- I found that the I didn't have enough camp interactions for any the romances. Even the easiest to romance -- Astarian suddenly developed standards and Lae'zel told me I had displeased her too often. (even if she was impressed by skills in battle)
I'm receptive to the critique that playersexual allows devs to get away with fewer companions -- (BG had 18 we need 18. period. full stop) -- but I'm with those saying that there isn't a good reason to believe Faerun has these hangups and plenty of reasons to think it doesn't.