I think dialogue responses will be somewhat limited to the Origin character's general personality/alignment. We can see a little of this for certain character types. For example, when talking to the Tiefling couple in the Grove, its usually a conversation about what creature comforts one imagines one will indulge in when they get to Baldur's Gate. As a Gith, none of those options were available to me other that remarking how foreign those things are - even not knowing what a cat was. I assume playing as Lae'zel, when Origin stories are complete, it will follow something similar.
Whether or not you can play the Origin characters as the polar opposite of their alignment - I think the writers still want to write believable characters, so we have to just wait and see how far these characters are able to stray. All the characters are written with aspects of occupying a moral gray area, and the most evil ones have a root cause that can be shaken.
Thank you for that info. It seems like an awful lot of resources will be poured into these Origins companions; I would be interested to see percentages on how many people intend to play them versus those who don't and I hope that those resources won't be at the expense of other things in the game which really could use a makeover or are missing from the game currently.