Did a full wipe on the second reinstall. No profiles, save files all of it and everything even related to the game completely erased. No improvements whatsoever.
Cleared up some space and ran a better defrag in case that was causing issues, minimal improvement.
Reduced graphics from ultra to medium again and the audio from high to low and strangely enough everything is still pretty sluggish but at least playable.
Most importantly load times are better and result in less crashes.
Not exactly "fixed" but at least better than it was.
Will continue looking into the cause for this though.
