To an earlier mention of Minsc, who is our big n strong but not bright, beloved ranger, doesn't he hate Vampires so would he hate Astarion and have a similar dynamic that Shadowheart and Laezel have where the two hate whatever makes the other happy?
If I remember it correctly, in BG1 he had Gnolls as favoured enemy, and in BG2 he had Vampires. His reasons for that are long past, but he should still be quite unwelcoming of a Vampire in the party. If Astarion explains to Minsc that Vampire spawns are miniature Vampires not at all from the giant space, and thus not a danger, it may fly.
