I guess the question I have about this is why do you hope CDPR don't cave? If it's made explicit she isn't bi and the male/female Judy romance is non-canon would it still bother you players are able to access it? For myself it's the Panam relationship I'm locked out of and I have a suspicion the only relationship they'll change is Judy's. That change would never affect me but if they were to shift Kerry's relationship I'd never really notice his character made less sense if the decision were left in the players hands. But it would be nice for me if Panam got a meta dialogue pick where it says "She's going to reject you because she's straight. Do you want to break the narrative slightly to make Panam bi?" that only appeared if I selected the appropriate option in a menu.
There's not a great deal I can add that I haven't already said; I think it dilutes the character and makes them more vague, especially if you can just flip a switch to make them something else. As Frumpkis pointed out, there's already an established back-story both with her current love life and her childhood, the significance of which is very significantly diminished by a personality change of that magnitude.
I suppose there's also the RL parallels where some people think that approach also works with real people, which isn't relevant to a game but makes me feel a bit icky.
Edit: but worse than all that, I just saw someone suggest Nibbles be replaced by a different "less ugly" cat. D: