I am doing a test run of the game with my 3 custom characters and Lae'zel using only D&D 5e rules to the best of my abilities. I am at the hag's house, and so far the game is going very well.

For example, if I drink a potion, I restrict myself from using an Action. Same for Disengage. I don't throw barrels. I eat food periodically, but only when full health, pretending to stave off exhaustion. I don't use Jump to bypass difficult terrain and then attack.

It not only can be done, but I'm telling you it works. Even though enemies cheat and use potions and disengage as Bonus Actions, I can still beat them. The game is, of course, more challenging, but it clearly can be done, and it definitely makes the game more fun for me. I find myself using potions more, I use more strategy, I use short rests more, etc.

So it can be done, Larian. It does work, and it is rewarding.