One thing I haven't seen discussed is the fact that you can see your odds of success when you target an enemy. In DnD, you don't know off the bat your odds of success and have to work it out for your self by trying your spells or attacks. If I want to be as effective as I can in combat, I can (in BG3) cycle through my spells and attacks, aiming each at an enemy, and decide which one is most effective.