I would say that larian has a much more difficult task to balance matches correctly.
The DM can adapt to the group on an ongoing basis by appropriately selecting the risk.
This cannot be done in the game. How to balance the game when you have no idea what the player will have in the team.
A player may as well have a team consisting of only combat classes that do not require much rest, or a team based entirely on classes that require more common rests.
Certain enemies will, of course, be a much greater threat to one type of team than to another.
Do you see where the problem is? Of course, the composition of the team itself is not the only thing that the creator has to take into account.
Larian brought this upon themselves. Introducing lop-sided mechanics. Some folks do misunderstand the CR system IRL, but it's not that difficult to understand. It's rather easy to balance as well (With the understanding that multi-attack / pack tactics can murder a low-level party).
Introducing lop-sided mechanics was always going to make balancing more challenging. Especially when depriving the player of reactions.