No, no problems on hitting, the stealth, attacking from shadows and attacking people in shadows can reduce hit chance. You can see the % chance to hit before attacking to find out what is messing you up, just activate a ability and highlight the target. Bottom right will have a combat log of attacks to see what's going on also.
enemy npcs have been adjusted already so they have lower armor and higher health to make it a tad easier to hit.
d&d games all have this, from Baldur's Gate 1 to Neverwinter nights 1, if you really did play a d&d video game you have missed before. 5e is different than say 3.0-3.5 but the core concepts are all their.
Edit* if you want advice from the community you could post a pic of your main character for his/her stats.
I rarely get above 45% on my hit chance. The most I've got is 85% with the Wizard fella on high ground. I'll give you an example of a fight that just took me 20 minutes to complete. The reason it took 20 minutes to complete was because it took five attempts with reloading to score a hit on a standard, non-boss Goblin, and when I did hit, I hit for a paltry 3 points, and that was just on one character. Not a single character on that turn hit the first time, all took several reloads before I did. Don't tell me that's normal, this game is not going to be remotely enjoyable if that stays. I've been PC gaming for almost 25 years and gaming in general for a lot longer and I have never once come across a game with a hit rate this low, and RPGs are one of my favourite genres. I can honestly say that if this continues I'll be putting the game down, and filing for a refund from Steam. This is just not enjoyable.