Star Wars: KOTOR, you're on a ship that's being attacked and have to fight your way to an escape pod.
Mass Effect 2:
The Normandy is destroyed, Shepard too... but oh thank Deus ex Machina as Cerberus retcons that horrible nightmare.
The Outer Worlds:
You are a being unfrozen from a long journey through space to find out your escape pod landed on your liaison.
I get the feeling Larian went with a more typical sci-fi beginning than high fantasy.
