I've came to the conclusion that this is probably a matter of presentation more than mechanics for Larian.
To be more explicit, I think that what they think is more or less: if we are going to implement reactions, they need to look "sleek and cinematic" in line with the rest of the game rather than just being a crude and unappealing "YES OR NO" pop-up over-impressed on the screen on a regular basis.
I'm honestly not sure how I'd solve this. I've been trying to imagine ways they can do this and "make it look good for the casual player", so to speak.
"Breach mechanic" from
Chimera Squad comes to mind (time stamp 00:44), but I wouldn't want whole zoom in, everytime I need to make a decision. I am sure they could make it look dynamic, while giving players all the time in the world to make the decision. A nice "Woosh" sound, some freeze animation of enemy in action, and your character readying for response and it's all cool again.