Could be designed as a future mod by community or we can also dream about a specific mode like in DOS2 (with Epic mode if I remember well).
What more are you talking about exactly when it comes to D:OS2?
If you just mean difficulty modes, then those will likely be there when the game launches - some form of Ironman might also be there. I am unaware of D:OS2 adding any additional mechanics, and things like Day/Night cycle are unlikely to be implimented in any capacity.
