First off, I really loved DOS2 and while I haven't played the original Baldur's Gate games I have played and enjoyed, other Bioware games. I love the RPG genre and I enjoy BG3. My problem however is that when origin characters become unlocked they will immediately have a much more impactful story than a custom character. This is what happened in DOS2, where a custom character has basically no story compared to the origin characters, and even then if you're not playing Ifan or Fane you have almost no connection to the main story.
My other problem is that I will always have a stronger connection to someone like Garrus or Morrigan far more than someone like Fane or The Red Prince, in part because while I can influence their character I am not playing as that character. I like Shadowheart and Gale, but I don't want to play as them, I want them to be my companions. That goes for all of the BG3 characters. Right now it feels like if my character didn't exist, nothing in the world would change. Unlike Mass Effect where the events are because the player character had direct involvement in the story.
Now I'm not asking Larian to add a game-long character quest for every backstory or anything, and their recent update that gives you inspiration for acting to your backstory is a good start. But I am asking them to let the other characters be companions and not playable characters. Let the custom characters have some actual weight added to the story and react to the world around them like in the old Baldur's Gate games. DND is a lot about making your character and having them be shaped by the world around you, not picking the characters made by the DM.
My last complaint is that letting the origin characters be playable forces one of two things to happen. Either they lose all of their personality because they are limited by what you can say, or you are encouraged to pick a specific dialogue choice because it had their name next to it. I would much rather be my character with them as good, well-written companions, who react to what I say and do rather than a husk of their former selves when I play as them.