I perfectly happy with a Vampire Spawn whose captivity has put him into a state of cartoonish arrested development, he wasn't a sympathetic person to begin with and being a victim doesn't just change him into one.
Astarion was the guy who went "So I kicked in the head until he was dead hyeh ha ha ha"
As for the 'humor' I'm not sure, comparing it to the old games I'm not sure how it stacks up. The humor could be all over the place, I think it has more to do with the kind of anachronistic way everyone treats the world they live in. Kind of like the characters in the Force Awakens, their perspective on the Star Wars universe was more like how the audience views it than how people who actually lived there would. Am I making sense?