Very easy. Limit inventory size + weight. And fuck <<auto sending>> stuff wherever. You want QUALITY OF LIFE?!?! Whats the point even moving around exploring? What a pain, clicking everywhere. Just make EVERYTHING AUTO.
The more quality of life people wants, the worst the <<<RPG experience>>> game exponentially gets.
You can still keep all your facorite JUNK items in the world for your <<<immersion>>> (though I think these should not even exist in the game...you didnt have spoons, plates etc...in BG2) yet make players THINK on what to carry based on their characters stats and class. Its an RPG after all.