Just some things I've noticed:
Some cutscenes have been lagging even when I lower the graphics settings. This has never been a problem for me before.
The characters' faces are a little more blurred than usual? Almost like the DOF has them a little out of focus. It stays this way even when I disable DOF though.
The animations in Astarion's first scene are broken. He floats off the ground for a moment before sliding over to the side of the screen. Then his eyes are stuck looking to the right when he talks to you.
Some dialogue is broken as well. Characters react as if you've chosen a dialogue option even if you haven't because none appeared. I noticed that in the Astarion bite scene he acts as if you're grabbing a weapon even if you don't choose that option.
And I don't know if this was intentional, but your companions tend to stand with their bodies angled away a little in cutscenes now. They have to turn their heads a bit to look at you. It's subtle so I'm not sure if it's a bug or a deliberate change that was made. To me it seems off though.