Yes. Unfortunately it doesn’t take much to confuse and loose our poor companions. I found them refuse to follow even is simplest of situations (like moving over beams in gobbling hideout). They also love climbing ladders back and forth if they are near one - climbing seems to be one action, so they can’t turn back halfway through if they start climbing one. If you go too far, pathfinding wont work and companion will stay there. Jumping is just a mess.

In case you don’t know about it, you can set up keyboard shortcut for linking-unlinking all companions. It comes handy when you have to babysit and lead character one by one.