What makes this more complicated is that carry weight is used to limit your inventory options. Without it the player can carry a bunch of explosives (barrels and stuff) which is a bit of a cheat. Loaded dice is a bit of a cheat too, I guess...
This brings us back to asking what is quality-of-life and what is a cheat. The developers could leave a way to access developer options (I remember doing this most recently in Sims 4 from the console) which is basically "cheat mode". Or we could rely on this feature being included in a mod. I understand why anyone would want to turn of encumbrance but making it a togglable option seems out of place, you know?
Accessing developer options seems most appropriate, I think, in this case. It lets you know that you are breaking the rules - tipping the balance of the game's difficulty in your favor - but the ability to do so is there if you want it. Now that I think about it, does anyone know if there is a console we can access in the game in it's current state? I just realized that I haven't even tried to do this yet.