I'd say there is, though I think there are some issues due how time mechanics currently work in the game. For example, on my second playthrough of Grymorge the party went there asap, skipping most of the Underdark. By the time they've arrived at the myconid village, Thulla
died and was turned into a spore servant. (Also managed to get Nere killed by the poison that one time. :D)