The crafting system and random detritus was the worst part of Witcher crafting. I can't remember from NWN.
I'm playing Solasta and I'm digging the system there. It tracks the recipes you have learned, which ones you can make with the ingredients you have, and which ingredients you are missing. I don't particularly care for managing my inventory, but at least I CAN just go around merrily picking up plants and stuff. Although I'm never quite sure what might be a needed ingredient down the road and which is sellable loot. I see the "Ingredient" tag on the item, but not sure if I can always trust it.
What I liked about crafting in D:OS, I was being able to make weapons I couldn't buy or find. They weren't Specialist flashy, but the damage was amaze-balls. Then they ditched it in D:OS II.

Joe