Similar crash upon save here.
I thought the issue was tied to messing about with the inventory. My guess was that backpacks within the inventory (which I use to sort potions, keys, scrolls etc...) are so bugged that you can place things into them but will crash the game upon save if you retrieved those items. Reading this thread shows I'm probably wrong, but there's definitely an issue with saving.
Had to restart a run 23 hours into playing with the bard because the game won't save at all. Thank god for the addition of gnomes to make the 2nd run interesting.
