If anything the combat should theoretically be more consistent because there are always improvements and new features being made with fixes being rolled out for things that didn't work as they should be. But as someone who plays extensively... no, I can't say there is any difference in combat.
The only combat scenario that has always been a bit challenging for me is the Githyanki patrol, where the fight can either go completely your way or completely opposite. I really hate that Greatsword Gith that spams Sleep 4 times in a row.