Ladders should be useful choke points.
1.) You should be able to block off ladders by positioning a character at the top/bottom of ladders
Once you're at the top, you can simply destroy the ladders, then opponents can only get up with spells like Jump or Misty Step and use ranged weapons.
Someone in a different thread about vertically mentioned how in Solasta(haven't played it) you can aim aoes like fireball at different heights so as to avoid friendly fire in the blast radius.
I do hope more is planned for Larian's implementation of vertical control and usage. Just being there for shoving really is a waste of the game's vertical space.
Oh dear, there are probably bugs inevitable. I can already see burning surfaces hanging in the air...