I always swear to drink it, accompanied by the option that it won't come to that when a companion calls us out. Since I would rather die by my own hand on my own terms than go through the worst imaginable pain ever and die, only to give birth to another creature and cause even more death down the road.
Now that I think about it, it kind of reminds me of Ellen Ripley in Alien 3

Even though I doubt we will fully transform in the full game as none of the other True Souls have and they've had the tadpole far longer than us. At worst I imagine once we become True Souls from overusing the tadpole, we will be mindcontrolled during certain events.