If the Dead Three are involved, I wouldn't be against the idea that we (the tadpole-infested PC) are already dead as the game starts, given the game specifically starts with the insertion of the parasite, and only then shows our perspective, after which it asks "Who are you?" The Netherese-modified tadpole did eat our brain, just not in the way it usually does, because modifications. Jergal follows us around 'cause we are half-dead tadpole hybrids made from Mindflayers and Netherese experimentation. It actually explains why "THE BLADE OF FRONTIERS," or "THE WIZARD OF WATERDEEP," or "MINSC" are level one... they're technically dead, but the modified ceremorphosis preserved their consciousness and personality. It explains why none of the usual vampire stuff applies to Astarion. It then gives us a very, very vested interest in the activities of the Gods of Death.
On the other hand, doesn't explain Raphael's offers, so... maybe not.