The problem with a lot of games that claim to be replayable is that you usually have all the information after one playthrough, the only thing that makes a second playthrough of a game really meaningful is if you don't get all the information about the story just from playing through it the first time. Just having a point near the end where you get to choose between three endings isn't it, but only getting three distinct endings based on what you accomplished during the first two acts is.

If all the questions of Baldur's Gate 3 are answered after one playthrough then there isn't much incentive to go back in, that goes for the companions and for the main plot.