If I was going for an Origin character, I'd go Lae'zel accompanied by Shadowheart, Karlach and Wyll.
Shadowheart to me screams like she's the main character of the story and Lae'zel right behind. So I'd go with her for more story insight, but I love her as a companion so I'd go as Lae'zel.
However I will 90% chance go my own character accompanied by Shadowheart, Lae'zel and Karlach.
