If Kingmaker/WotR were Owlcat's take on BG, this looks like Owlcat's take on Wasteland 2-3/the Shadowrun RPGs in the WH40k setting. It *seems* quite neat so far, actually. The grid- and turn-based combat and a custom ruleset seem like a good fit instead of having them try to adapt Pathfinder again. I really liked Mechanicus but found it a bit on the easier side, and this - if not botched again - looks quite promising.

As far as similarities to their previous titles - it is the same framework and engine features, after all. It's a complaint that falls into the same category as "BG3 is just a D:OS reskin", which it isn't, and this doesn't appear to be just Kingmaker/WoTR repurposed either. Time will tell, I suppose, the main concern is, as usual, its release state.