The people writing a video game should try to write as many permutations as they can before it's ripped out of their hands.
I think one of the reasons people had trouble accepting Mass Effect 3 is because of how ungainly some of the ways it dealt with possible world states from the previous two games. That isn't to say that Mass Effect 3 didn't have some places where it did well. I think a lot of that is from how little Mass Effect 2 did to advance the overarching plot of the trilogy.
If there ever is a Knights of the Old Republic 4, I personally don't think they'd adhere to The Old Republic canon. They made Revan a man because that's probably what %70 of the people who played SW:ToR made, and the MMO couldn't have it both ways. They made the Exile a woman because when SW:ToR II came out gaming was more sex conscious, and gaming wasn't being treated as stereotypically a young boy's hobby; and because they'd already made the protag of the first game a dude.
for some context,
https://www.gameinformer.com/b/news...ffect-players-choose-female-shepard.aspx Knights of the Republic II came out in 2004, the Star Wars MMO released in 2011, and the Revan expansion game out in 2014. I don't know when Revan was definitively made male.