DA:I already had a trans male (barely not companion) character. Pretty well received.
Yes, good point. Krem certainly garnered a fanbase and is an example of successfully introducing a trans character into a fantasy RPG. Bioware also have at least a couple of less successful examples of fortunately smaller cameos for (possibly) trans characters in DA:2 and MEA that now spring to mind, but at least they are trying and are willing to learn from their mistakes!
And as you alluded to in your post above, it helps when the companies making games have a diverse and representative staff who can help make sure that LGBT+ characters in their games are portrayed realistically.
"You may call it 'nonsense' if you like, but I've heard nonsense, compared with which that would be as sensible as a dictionary!"