I would love some gender-swapping 🥰, that would entice me to :
1) Play an Origin character. For instance : a female Astarion, Gale or even Wyll.
2) Romance other candidates and not just Astarion 😅, such as male Shadowheart or potentially female Gale.
I don't think things needs to change with the writings.
However, I do think the main issue would be :
1) Adding Voice Acting for all those characters.
2) Changing the lines (Writing + Voice Acting) of characters using gendered pronouns to switch to the other polar opposite gender (assuming binary nature).
3) Adding new animation for the now infamous to-be-sex-scenes 😅 (please don't let this be another thread about this, please don't, please don't, please don't...).
Those would probably require a lot of ressources.
So, I don't really have hope that this could actually happen.
But, it is absolutely a fun and interesting thing to think about 💜!
And I agree, that would be pretty cool 😊!
