In TT there's a trap where the odd player sometimes thinks they're the main character and it causes problems at the table. This is because the game's true focus isn't any one character, it's the _party_.

It's true, the MC isn't a vampire, doesn't have a devil patron, deity lover, lich empress or secret cult mission. MC is more bland and generic. We're no longer playing the Child of Bhaal confronting our megalomaniacal half-brother. (Although there remains the question, why exactly was Tav snatched up? One of many or specific mark?)

Me personally? I'm a little done playing chosen ones, so I've got that bias. I like the world setting where MC dies and things continue... badly it seems.

Back to OP, MC dies and the party can't rest. That's kind of perfect. The huge ego origin characters can't agree anymore and disband. Probably all failing individually.

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One little doodle I do as a DM is paste character portraits and draw connections to make a relationship map. You can also ring the party with a few important NPCs. The arrows are widened or narrowed to show strength of connections. Anyway, this little activity shows the characters most immersed in the setting, you guessed it - the de facto party (co)leader. The real purpose is to expose weak characters - and work to fix it up with those players.