Nah, I definitely don't want a loot radius button.

I like the immersion of picking and poking things. Something you learn by mid-late Act 1 is that there's a stupendous abundance of treasures. Yes, I've collected it all through multiple play throughs and to me the game is more fun collecting hard when poor, then looting selectively when rich.

Seems to me Act 1 has about 200% loot so that casual playthrough sees you well-enough set up for Act 2.

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I did one play through where I optimized Astarion to steal from traders after each rest. I had them all lined up in order with an MO. Gold quickly ballooned to 20k+ and everyone was laden with nothing but the best. At that point I got selective about what was worthwhile stealing to reduce effort-of-clicking. Fantastic experience - once.