While it is true if you traveled 4,000 years in the past people would look different, it wouldn’t be quite like that. On average most peasants would look a lot older than we’d think they were and would have worse skin. Nobles and rulers might look better off depending where and when. And there would be more people with conspicuous deformities (like Solas I guess) that today doctors could take care of. And of course people on average were much shorter, so if you are 6 ft tall you’ll very much stand out. But people would otherwise look the same as they do now. Human skull shape hasn’t changed for a few hundred thousand years.

Disease wise we would probably be fine. We’ve inherited thousands of years of genetic immunities because we are the descendants of people who survived those diseases. Natural selection at play there.