This is still an issue in 2023. The game freezes every few minutes with 100% CPU usage.
I'm running Win 10 pro (latest version)
32GB RAM
NVIDIA GF RTX 3060 12GB memory

I've performed the following:
3 complete reinstalls and rebooted after each uninstall/reinstall.
6 file integrity verifications.
Disabled the Steam overlay.
Disabled cloud save.
Gave the Larilauncher.exe admin rights.
Gave the bg3.exe and the bg3_dx11.exe admin rights.
Disabled mute sound when active.
Disabled Autosave.
Switching from Fake Fullscreen to Fullscreen had no effect and still froze.
No Framerate Cap enabled.

Today when I attempted to launch the game through Steam, the Larian Launcher for BG3 was completely blank and I had to use the bg3.exe launcher instead.

I'm not sure what else I can try at this point. This is my first game by Larian and I'm really enjoying Baldur's Gate III. The constant freezing issues are almost enough to cancel out that enjoyment when every few minutes everything just dead stops and rips you right out of the immersion.