Yes, the misses I mentioned were always from stealth with Sneak Attack, with 17 Dex, therefore I noticed it as a waste. I don't care for misses with normal attacks. But I'm only at lvl 3 now, so I have not much experience or statistically valid data. And it is not a problem of the Rogue especially, so I do not spend too much attention. All classes miss more without Karmic Dices and the casters are hit worse because if they miss it's no damage and one slot less. My last fight against the Gith for example (Shadowheart, Gale, Wyll, my Light Domain Cleric) almost ended badly because of lots of misses, at the end the lonely survivor (my char) had to kill the last Gith with his bow, as all slots were gone. I like it without Karmic Dices, the AI fares better this way.
