Many of the same things as other people, although I'm sure none of this will be available on release:

1. conversation die removed option

2. granularity in difficulty options (incoming damage, outgoing damage, critical hits, etc, think Pathfinder wotr)

3. options for more players

4. GOOD modding tools ala Skyrim, not just textures and small gameplay tweaks, I want to see full scripting, fully-voiced new campaigns, etc

5. no Larian 'we'll be forcing you to be a certain level at certain points in the game by limiting xp in Acts'.