Let's play the what it has a good chance to be and what it wont be. Based from memory of what I read when it was first announced, and partially from what I was curious myself:

Good Idea: Unannounced playable characters from BG1 or BG 2: Viconia, Jahira, Minsc (am I the only one wanting Edwin(a)?)
Bad Idea: Unannounced playable Characters from BG Enhanced Editions/Dragonspear: Because few (no one?) want to play as M'khiin, Baeltoh, or Hexxat

Good Idea: Bringing back characters that everyone enjoys from the previous games/FE lore: Drzzt, Elmenster, Boo, etc
Bad Idea: Bringing back Mizhena

Good Idea: Bringing back play elements from DnD BG1/2: active combat, rolling characters, and other DnD elements that used to be present in the game
Bad Idea: Trying to teach people Thac0.

Good Idea: the characters/npcs have lineage connected to the game: tadpole resistance= Bhaalspawn lineage, Bhaal is the Absolute
Bad Idea: the characters/npcs have lineage connected to the game: Wilson = Owlbear's daddy